Particle Size Independent Variation of Bulk Excipients presents a study using the FT4 Powder Rheometer^® to identify and quantify variations in batches of excipients that contribute to differences in in-process performance. This enables a design space of acceptable raw material properties to be established, which is an essential part of Quality by Design.

Sachet Filling is widely employed in the food and pharmaceutical industry and it’s imperative that the process produces consistent, uniform fill throughout an entire production, with low weight variation and high content uniformity. This study illustrates how formulations can be optimised by using the FT4 to identify the properties of powders or blends that are conducive to efficient processing and a high quality final product.