In a recent Q&A with OINDP (Orally Inhaled and Nasal Drug Products), Jamie Clayton, Operations Director at Freeman Technology, discusses dynamic powder testing and why it is valuable for DPI development.
'Powder behavior is highly dependent on the conditions to which the powder is subjected – for example, think of how aeration or consolidation transform flowability. Therefore, to optimize a DPI formulation, we need to characterize behavior across a range of conditions. To fully characterize a DPI formulation, we need to consider the powder’s behavior in a low stress state, the impact of compression on the powder, and the formulation’s aeration performance.'
Please click here to read ‘Using Dynamic Powder Testing in DPI Development’.